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Here are the 55 US AI startups that raised $100M or more in 2025

Here are the 55 US AI startups that raised 0M or more in 2025

The AI Industry: A Year in Review

The AI industry has experienced significant growth and investment in recent years, and 2025 was no exception. With 49 US-based AI startups raising $100 million or more, it’s clear that the industry is continuing to attract attention and funding from investors. In this article, we’ll take a closer look at the AI startups that raised significant funding in 2025 and explore the trends and insights that can be gleaned from this data.

December Funding Roundup

In December, several AI startups announced significant funding rounds. Mythic, a company that builds power-efficient compute for AI, raised a $125 million venture round led by DCVC. Chai Discovery, which builds AI models for biotech and drug discovery, announced a $130 million Series B round that valued the company at $1.2 billion. Fal, a generative media platform, raised a $140 million Series D round led by Sequoia, and Unconventional AI announced a $475 million seed round led by Lightspeed Venture Partners and Andreessen Horowitz.

November and October Funding

In November, Genspark, an all-in-one AI workspace platform, announced a $275 million Series B round, while Luma AI, which builds models used for photo and video creation, raised $900 million in a Series C round. In October, Fireworks AI, a platform that allows users to build AI applications using open source models, raised a $250 million Series C round, and Uniphore, an enterprise AI startup, raised a $260 million Series F round.

September and August Funding

In September, Periodic Labs, which is building an AI scientist, announced a $300 million seed round, while Cerebras Systems, an AI infrastructure company, raised a $1.1 billion Series G round. In August, EliseAI, a healthcare and housing automation platform, raised $250 million in a Series E round, and Decart, an AI research lab, raised $100 million at a $3.1 billion valuation.

July and June Funding

In July, Fal raised a $125 million Series C round, while Ambience Healthcare, which is building an AI healthcare operating system, raised a $243 million Series C round. In June, Abridge, a healthcare AI unicorn, announced a $300 million Series E round, and Harvey, which builds AI tools for the legal industry, raised a $300 million Series E round.

May, April, March, February, and January Funding

In the first five months of 2025, several AI startups announced significant funding rounds. In May, Snorkel AI raised a $100 million Series D round, while LMArena raised a $100 million seed round. In April, SandboxAQ closed a $450 million Series E round, and Runway raised a $308 million Series D round. In March, OpenAI raised a record-breaking $40 billion funding round, and Nexthop AI announced a $110 million Series A round. In February, Together AI raised a $305 million Series B round, and Lambda raised a $480 million Series D round. In January, ElevenLabs raised a $180 million Series C round, and Hippocratic AI announced a $141 million Series B round.

Conclusion

The AI industry continued to attract significant investment in 2025, with 49 US-based AI startups raising $100 million or more. As the industry continues to grow and evolve, it’s likely that we’ll see even more innovative AI startups emerge in the coming years. For more information on the AI startups that raised significant funding in 2025, Here

Image Credit: techcrunch.com

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